Clinical session
Room: Maas
Room: Rijn
- Parallel abstract session 1: Lifestyle (interventions) and risk for diabetesChair: Dr. Marieke Blom
09.45 – 10:00
A closer look into the impact of a six months personalized combined lifestyle intervention on physical activity, heart rate, sleep and metabolic resilience
S. Wopereis (Leiden)
10.00 – 10:15
The association between ultra-processed food intake on body composition and metabolic parameters after a combined lifestyle intervention
K.A.M. Geurts (Rotterdam)
10.15 – 10:45
Objectively-determined chronoactivity and type 2 diabetes risk: a prospective study in UK Biobank participants
Q. Feng (Leiden)
10.30 – 10.45
Assessing the effect of an intensive lifestyle intervention on healthy and unhealthy behaviors in daily life for individuals with overweight and obesity
E. Vanbrabant & J. Hesen (Maastricht)
10.45 – 11.00
A real-world feasibility study for an e-health blended personalised lifestyle intervention to affect the risk of developing type 2 diabetes in people with prediabetes
L.G.P. Peters (Leiden)
Room: IJssel
- Parallel abstract session 2: Beta cell functionChair: Dr. Willem Hoogaars
09.45 – 10.00
Beta cell-specific 3’UTR modulation by genetic variants during type 2 diabetes reveals miRNA regulation of PTEN
T.J.J de Winter (Leiden)
10.00 – 10.15
Adipose stromal cell secretome for a sustainable microenvironment within a subcutaneous polymeric scaffold for insulin-producing cell transplantation
A.M. Smink (Groningen)
10.15 – 10.30
HNF4α Expression Differs Between Fetal and Adult Human Beta Cells
R.D. Hauck (Leiden)
10.30 – 10.45
Hypoxia-inducible pathway mitigates mitochondrial dysfunction in pancreatic β-cells
R. Fagundes Rosa (Leiden)
10.45 – 11.00
MAP3K15 variants and their role in in modulating diabetes risk: functional analyses and protective effects in knockout mice
D. Struik (Groningen)
11:00 – 11:15
Developing a vascularized islet-on-a-chip model
M.S. van Agen (Leiden)
Room: Lek
- Parallel abstract session 3: Liver biologyChair: Prof. dr. Vera Schrauwen-Hinderling
09:45 – 10:00
Pharmacological inhibition of fructose metabolism reduces liver fat and improves insulin sensitivity in participants with MASLD
E.J.C. Koene (Maastricht)
10:00 – 10:15
Dynamic 3D Deuterium Metabolic Imaging in the liver at 7T
M.M. Konig (Utrecht)
10:15 – 10:30
Liver Fibrosis as a Predictor of Cardiovascular Risk in Patients with Severe Obesity: Insights from the Assisi Study
A. N. Saidi (Rotterdam)
10:30 – 10:45
Advanced MASLD Fibrosis: Low Number-Needed-to- Screen in multiple lines of care
S. Driessen (Amsterdam)
10:45 – 11:15
Opportunities for young researchers offered by Diabetes Fonds
Mariette Boon, Erasmus MC
Frieda van der Jagt, DiabetesFonds
Room: Waal
- Parallel abstract session 4: Clinical track: advancing diabetes careChair: Dr. Joëlle Oosterman
09.45 – 10.00
Metformin intolerance multicenter Switch study from immediate release (IR) to extended release (ER) formulation
O.W.F. Natan (Utrecht)
10.00 – 10.15
Individual Albuminuria Lowering Effects of Dapagliflozin in Patients with Type 2 Diabetes: A Series of Decentralized N-of-1 Randomized Placebo-Controlled Trials
J.M. Beernink (Groningen)
10.15 – 10.30
Advancing Pregnancy Care for Women with Diabetes: A Prospective Registry Cohort in the Netherlands
V. Duwel (Amsterdam)
10.30 – 10.45
The Diabetes Body Project: Acute effects of an eating disorder prevention program for young women with type 1 diabetes: a multi-national randomized controlled trial
M.H.C.L. Hennekes (Amsterdam)
10.45 – 11.00
Impact of pharmacological and dietary modulation of fructose, glucose and saturated fatty acids on serum sex hormone-binding globulin levels in humans
H. Chen (Maastricht)
11:00 – 11:15
Implementation of Lifestyle in Standard Care for Type 2 Diabetes: A Qualitative Study
E.A.G. Hietbrink (Enschede)
Room: Maas
- 09:45 - 10:15
Type 1 diabetes en zwangerschap; hoe kan het beter?
- 10:15 - 10:45
Stress door diabetes
- 10:45 - 11:15
Wekelijkse insulinetherapie: binnenkort beschikbaar?
Room: Rijn
- Parallel abstract session 1: Impact of lifestyle & dietChair: Dr. Wilrike Pasman
11.45 – 12.00
A fibre-rich Dutch healthy diet to improve cardiovascular risk profile in people with type 2 diabetes: a randomized controlled trial
I. van Damme (Wageningen)
12.00 – 12.15
Exploring fructose kinetics in Type 2 Diabetes: preliminary data of 20 ERIE-trial participants
F.H.M. Westerbeke (Amsterdam)
12:15 – 12:30
The effect of extended personalization to a combined lifestyle intervention program in Dutch primary care
D.J. Smid (Leiden)
12.30 – 12.45
The association between ultra processed food intake and stress and eating behaviour in a combined lifestyle intervention
R.E.H. Meeusen (Rotterdam)
12.45 – 13.00
A fasting-mimicking diet programme reduces liver fat and inflammation/fibrosis measured by MRI-derived biomarkers in patients with type 2 diabetes
E. van den Burg (Leiden)
13.00 – 13.15
Feasibility of following a fasting-mimicking diet program in persons with type 2 diabetes in primary care – a mixed methods study
M.P. Schoonakker (Leiden)
Room: IJssel
- Parallel abstract session 2: Insulin signalingChair: Dr. Dicky Struik
11.45 – 12.00
Cannabidiolic acid mitigates postpartum development of metabolic dysfunction-associated steatotic liver disease in a mouse model of gestational diabetes mellitus
J.K.Kruit (Groningen)
12.00 – 12.15
Glycodeoxycholic acid inhibits primary bile acid synthesis with minor effects on glucose- and lipid homeostasis in humans
E.C.E. Meessen (Amsterdam)
12.15 – 12.30
Fetuin B-related changes in adipose tissue transcriptome and plasma proteome are related to metabolic and insulin signaling
R.C.R. Meex (Maastricht)
12.30 – 12.45
Impact of Elevated Branched-Chain Amino Acid Levels on Insulin Signaling and Metabolic
F. Vanweert (Maastricht)
12.45 – 13.00
Myokine secretion and metabolic pathways under resting and contractile conditions in primary human myotubes: a matter of oxygen?
L. Mennens (Hasselt/Maastricht)
13.00 – 13.15
Different risks of type 2 diabetes between subtypes of insulin resistance
J. van der Velde (Leiden)
Room: Lek
- Parallel abstract session 3: Inflammation and stressChair: Dr. Julia van Heck
11.45 – 12.00
Methylglyoxal has no direct effect on immune cell recruitment or activation but is involved in trained immunity
K. Wouters (Maastricht)
12.00 – 12.15
Unraveling the Impact of Daily Life Stress on Glucocorticoid Regulation and Cardiovascular Disease
M. Boon (Rotterdam)
12.15 – 12.30
Hypoglycaemia levels of adrenaline elicit an inflammatory response in people with or without T1DM
I.F. Mustafajev (Nijmegen)
12.30 – 12.45
A single experimental hypoglycaemic event induces acute and prolonged transcriptional changes in circulating monocytes of people with type 1 diabetes and healthy controls
M.S. Hendriksz (Nijmegen)
12.45 – 13.00
Hair glucocorticoid levels and the metabolic syndrome: a role for age?
S. Kuckuck (Rotterdam)
13.00 – 13.15
Obesity affects the adipocyte glycosylation machinery and N-glycan profiles in mice
Z.Q. Zhang (Leiden)
Room: Waal
- Parallel abstract session 4: Cardiometabolic complicationsChair: Dr. Anouk Gijbels
11.45 – 12.00
MASLD and metALD: the number of cardiometabolic risk factors and the amount of liver fat in relation to the risk of type 2 diabetes and cardiovascular disease
J. van der Velde (Leiden)
12.00 – 12.15
A clinical dose of adipose-derived stem cells does not significantly affect atherosclerotic plaque in a streptozotocin-induced hyperglycaemia mouse model
A. Korn (Amsterdam)
12.15 – 12.30
The role of perivascular adipose tissue in the regulation of microvascular function in a mouse model of prediabetes
E. D’Alessandro (Maastricht)
12.30 – 12.45
Association of Arterial Stiffness with Whole-body and Tissue-specific Insulin Resistance and with Incident Diabetes: The Maastricht Study
J. Shen (Maastricht)
12.45 – 13.00
Associations of blood pressure with retinal arteriolar narrowing and urinary albumin excretion are modified by prediabetes and diabetes: The Maastricht Study
K. Wang (Maastricht)
Room: Schelde
- Parallel abstract session 5: Neurovascular complicationsChair: Prof. dr. Sicco Bus
11.45 – 12.00
In-depth pressure analysis of indoor versus regular custom-made footwear for people with diabetes and peripheral neuropathy
L.E. Vossen (Amsterdam)
12.00 – 12.15
Peak Plantar Pressure as a Prognostic Marker in Charcot Neuro-Osteoarthropathy
V.E.L. Milbourn (Amsterdam)
12.15 – 12.30
Exploring unknowns in footwear design for individuals with diabetes at moderate-to-high risk of ulceration: a knowledge gap analysis
I. Gigante (Amsterdam)
12.30 – 12.45
Reliability of a measurement protocol to obtain plantar pressure data in neuropathic diabetic patients using the FootWork Pro® Platform
D.J.J. van Gulick, (Amsterdam)
12.45 – 13.00
The effect of using a bone biopsy guided antibacterial therapy on remission of diabetic foot osteomyelitis: A randomized controlled trial
R.S. Lagrand (Amsterdam)
13.00 – 13.15
Quantifying Mechanical and Morphological Properties of Plantar Foot Soft Tissues: A Systematic Review of Methods and their Clinimetric Properties
A. Vicentini (Amsterdam)
Room: Maas
- 11:45 - 12:15
Recente ontwikkelingen in de NHG standaard diabetes mellitus type 2
- 12:15 - 13:30
Jaarvergadering DiabeteskamerAgenda Diabeteskamer ALV- Wijzigingen samenstelling bestuur
- Diabeteskamer reglement
- Dossier sensorvergoeding
- Lopende zaken/WVTTK
Room: Maas
Room: Maas
Room: Maas
- 16:30 - 17:30
Obesitas en leefstijlveranderingenThis Campfire session hosted by the jNVDO will start off strong with rapid-fire questions, followed by an interactive discussion on lifestyle, intervention and obesity by prof. Liesbeth van Rossum (professor in obesity), dr. Giesje Nefs (psychologist), drs. Nathalie Wilmsen (nutritionist Voeding Leeft), dr. Rick Meijer (internist), and Martin Landstra (patient).Come with questions, leave with insights – don’t miss this chance to be part of the conversation!
Room: Maas
- 17:30 - 17:40
Introduction
- 17:40 - 18:15
Presentation candidates
Room: Maas
- 18:30 - 18:45
Opening and winner of the award in 2023
- 18:45 - 19:00
Announcement and lecture by the 2024 awardee
Room: Waal
Room: IJssel - Breakfast served in the meeting room!
Room: Rijn
- Parallel abstract session 1: Diabetes and the microbiomeChair: Dr. Kristiaan Wouters
09.00 – 09.15
Using an in vitro large intestine model to identify fiber(s) able to induce a fermentation switch in the gut microbiota of individuals with obesity
T. van Deuren (Maastricht)
09.15 – 09.30
β-hydroxybutyrate Alters Cell Composition and Gives Rise to Bihormonal Cells in Human Pancreatic Islets
Y.S Chae (Leiden)
09:30 – 09:45
From Disruption to Recovery: Antibiotics, Dietary Fiber, and the Fate of Bacterial Membrane Vesicles in Human Metabolic Health
J. Verbunt (Maastricht)
09:45 – 10:00
Encapsulated autologous faecal microbiota transplantation may halt beta cell function decline in recently diagnosed type 1 diabetes mellitus in a single-arm trail
P. de Groen (Amsterdam)
10.00 – 10.15
Lactobacillus delbrueckii is associated with methylglyoxal levels in type 2 diabetes
O.I. Akinrimisi (Amsterdam)
Room: IJssel
- Parallel abstract session 2: Glucose variabilityChair: Prof. dr. Matthijs Hesselink
09.00 – 09.15
SAF is associated with glucose variability measured by continuous glucose monitoring – The Maastricht Study
N. Dimitropoulou (Maastricht)
09.15 – 09.30
How variable is the glycemic variability: analysis of CGM data over one year
E. Schupp (Nijmegen)
09:30 – 09:45
HbA1c Variability Score as a predictor for complications and mortality in patients with type 2 diabetes
S.E.M. Teunissen (Almelo)
09:45 – 10:00
Effect of Continuous Glucose Monitoring on Glycemic Control in Adults with Type 2 Diabetes
M. Jancev (Utrecht)S.E.M. Teunissen (Almelo)
09:45 – 10:00
Effect of Continuous Glucose Monitoring on Glycemic Control in Adults with Type 2 Diabetes
M. Jancev (Utrecht)
10:00 – 10:30
Opportunities for young researchers offered by Diabetes Fonds
Marleen Kunneman, LUMC
Roel Nahuis, DiabetesFonds
Room: Lek 2
- Parallel abstract session 3: Cardiometabolic complications continuedChair: Dr. Jeroen van der Velde
09.00 – 09.15
Cardiometabolic effects of the FGF-system in T2DM: studies in the postprandial state
L.A.M. Konings (Rotterdam)
09.15 – 09.30
Hepatic fibrosis determines cardiovascular risk in T2DM independent from other cardiovascular risk factors: Report from the AleCardio Trial
W.W. XU (Utrecht)
09:30 – 09:45
The food matrix affects systemic fructose dynamics and diastolic blood pressure: results from an open label, randomized, crossover study
M.A.J. van Oeteren (Maastricht)
09:45 – 10:00
Increased risk of incident stroke in people with type 2 diabetes is not mediated by microvascular dysfunction: pooled analysis of three population-based studies
I.L.M Steens (Maastricht)
10.00 – 10.15
Steatotic liver disease interacts with a polygenic risk score for VLDL clearance on hypertriglyceridemia risk: The Maastricht Study
Z. Ren (Maastricht)
Room: Waal
- Parallel abstract session 4: Glucose regulationChair: Prof. dr. Miranda Schram
09.00 – 09.15
Assessment of a 14-Week diabetes rehabilitation program for individuals struggling to attain target HbA1c despite advanced therapies: A prospective cohort study investigating glycemic control and psychosocial outcomes
A. Kooistra (Groningen)
09.15 – 09.30
Experienced blood glucose regulation after menopause: a cross-sectional survey in women with type 1 diabetes
E.M. Speksnijder (Amsterdam)
09:30 – 09:45
Metabolic and functional improvements 3 months after total knee replacement surgery
J. Most (Heerlen)
09:45 – 10:00
Comparison of glycemic responses following meal tolerance testing during early and late second trimester with oral glucose tolerance in overweight pregnant women
P. Arum (Groningen)
Room: Schelde
- Parallel abstract session 5: Beta cells: from psychology to physiologyChair: Dr. Alexandra Smink
09.00 – 09.15
Psychological health of people with type 1 diabetes, referred for pancreas or islet transplantation
S.D. Huisman (Leiden)
09.15 – 09.30
Beta cell mass as quantified by exendin PET/CT imaging is similar in individuals with and without remission of type 2 diabetes after Roux-en-Y Gastric Bypass
S. Tokgöz (Nijmegen)
09:30 – 09:45
Clinically compliant differentiation of human pluripotent stem cells into beta cells and enrichment of stem cell islets
B. Rajaei (Leiden)
09:45 – 10:00
Islets from older organ donors and the effect on transplantation outcome
E.J. Hammink (Leiden)
10.00 – 10.15
Improvement in Glycemic Control and Elimination of Exogenous Insulin Use in Patients with Type 1 Diabetes Infused with Fully Differentiated Islet Cells (VX-880)
E.J.P. de Koning (Leiden)
Room: Maas
Room: Maas
Room: Maas